Technical information by Dr Yaro Cletus (Veterinary Surgeon) for and behalf of Aviform Ltd
What determines the level of ingredients within Suppleaze Gold?
The level of key ingredients is formulated to match those used within published research..
For example, the typical daily 27g dose of Suppleaze Gold provides 11g (11,000mg) of Glucosamine HCL with published research based on 10g Glucosamine daily.
The same 27g of Suppelaze Gold provides 4g (4,000mg) of Chondroitin Sulphate with published research based on 4g Chondroitin daily.
The latest specification Suppelaze Gold now provides 10g (10,000mg) MSM per 27g. This is recognised as the recommended daily amount of MSM for maximum benefit.
Why is the daily feeding amount of Suppleaze Gold less than many other supplements?
Quite simply, Suppleaze Gold does not contain any fillers of bulkers. Just 27g of Suppelaze Golds provides the levels of each key ingredient to match those used in published research.
Aviform joint supplements will never contain unnecessary ingredients such as alfalfa, rice flour or calcium carbonate (limestone flour), all commonly used to dilute the important ingredients. As our joint supplements are both palatable and stable without such ingredients (two excuses often used to justify such inclusion), we don’t add them.
Some supplements have a typical daily dose of approaching 100g! This is either because the product contains fillers/bulkers or the ingredients levels are excessive in an attempt to look favourable in comparison tables. These products are very costly to buy/use and giving excessively high ingredient levels is at best ‘probably’ just wasting your money with little or no actual additional benefit.
How does each ingredient within Suppleaze Gold help?
Glucosamine HCL (not the less pure Sulphate)
Suppelaze Gold provides 11,000mg per 27g
The major building blocks of cartilage and for the biosynthesis of glycosaminoglycans. Delays the breakdown of and helps repair damaged cartilage
Glucosamine is the most well-studied ingredient in joint supplements.
Glucosamine is effective in relieving pain, sometimes in as short a time as 10 to 14 days.
An effective equine dose is 6,000 to 11,000 mg/day. The 10,000 mg dose is usually needed for horses that are being worked. This higher level is also recommended during the first week or two of any horse’s treatment, known as the “loading” period, which helps speed up results by getting a therapeutic level of the substance into the horse’s system.
Lower Molecular Weight
Suppelaze Gold provides 4,000mg per 27g
Help reduce pain and inflammation, improves joint function and slows the progression of osteoarthritis (OA).
Chondroitin Sulphate is a major structural component of cartilage, bone, and connective tissues. An effective equine dose is between 1,250 and 5,000 mg/day.
Glucosamine + Chondroitin combined
The most recent research is showing superior results for combinations of Glucosamine and Chondroitin, as contrasted to results when either substance is used alone.
Many other equine joint supplements combine these two ingredients but the dosage of one, or both, is low compared to the individual dosages. Suppleaze Gold contains the full clinical dose of both Glucosamine and Chondroitin.
Glucosamine and Chondroitin are the cornerstones of any joint supplement.
Suppelaze Gold provides 10,000mg per 27g
A naturally occurring sulphur compound, one of the major building blocks of glycosaminoglycans found in cartilage and it is an effective anti-inflammatory.
Hyaluronic Acid (HA)
At least 44% Glucuronic Acid level – the highest available
Suppelaze Gold provides 200mg per 27g
An essential component of cartilage and synovial fluid and acts as a cushion for bones as it resists compression and allows the joints to bear weight and oppose tension.
Glucosamine and chondroitin were being used in human arthritis patients before those ingredients were used with horses, but equine medicine was first when it comes to Hyaluronic Acid. It is an important component of both the cartilage itself and the joint fluid. Hyaluronic acid first appeared as an injectable drug in the 1970s. (It was actually on the black market from Europe and Canada for a few years before FDA approved its use in American products.)
Most recently, hyaluronic acid has been available as an oral supplement. Hyaluronic acid is particularly good for controlling pain, heat, and swelling. An effective equine dose is between 100 and 200 mg/day.
Addition of as little as 20 mg of hyaluronic acid to a glucosamine and chondroitin combination product may make a difference for some horses. In other cases, you will have to use the full 100-200mg dose
Suppelaze Gold provides 1,800mg per 27g
Contributes to normal collagen formation for the normal function of cartilage, as well as the protection of cells from oxidative stress.
An effective equine dose is up to 2,000mg/day.
There is a recent trend with some supplement manufacturers to add very high doses of Vitamin C as a unique selling point, probably because the ingredient is relatively inexpensive.
This is an ingredient where more is not necessarily better. Excessive amounts may even damage cartilage.
It’s worth noting a horse’s body is capable of manufacturing its own vitamin C.
What research do you have available for the ingredients within Suppleaze Gold?
Effects of hyaluronan alone or in combination with chondroitin sulfate and glucosamine.