Glucosamine HCL, Chondroitin, MSM, HA, Bioactive Collagen Peptides, Curcumin, Boswellia, Vitamin C. No fillers – No Bulkers.
Technical information by Dr Yaro Cletus (Veterinary Surgeon) for and behalf of Aviform Ltd
What determines the level of ingredients within Suppleaze VS?
The level of key ingredients is formulated to match those used within published research or the at recognised optimum levels.
How does each ingredient within Suppleaze VS help?
Glucosamine HCL (not the less pure Sulphate) 99% Pure | FEMAS Assured
Suppleaze VS provides 10,000mg Glucosamine HCL per 64g
The major building blocks of cartilage and for the biosynthesis of glycosaminoglycans, Glucosamine is the most well-studied ingredient in joint supplements.
Delays the breakdown of and helps repair damaged cartilage.
Glucosamine is effective in relieving pain, sometimes in as little as 10 to 14 days.
An effective equine dose is 6,000 to 11,000 mg/day.
90% Pure | FEMAS Assured | With a lower molecular weight for improved absorption.
Suppelaze VS provides 4,000mg Chondroitin Sulphate per 64g
Helps to reduce pain and inflammation, improves joint function and slows the progression of osteoarthritis (OA).
Chondroitin Sulphate is a major structural component of cartilage, bone, and connective Issues. An effective equine dose is between 1,250 and 5,000 mg/day.
Glucosamine + Chondroitin combined
The most recent research is showing superior results for combinations of Glucosamine and Chondroitin, as contrasted to results when either substance is used alone.
99% Pure | FEMAS Assured
Suppelaze VS provides 10,000mg MSM per 64g
A naturally occurring sulphur compound, one of the major building blocks of glycosaminoglycans found in cartilage and it is an effective anti-inflammatory.
Hyaluronic Acid (HA)
At least 44% Glucuronic Acid level – the highest available | FEMAS Assured.
Suppelaze VS provides 200mg HA per 64g
An essential component of cartilage and synovial fluid and acts as a cushion for bones as it resists compression and allows the joints to bear weight and oppose tension.
It is an important component of both the cartilage itself and the joint fluid. Hyaluronic acid first appeared as an injectable drug in the 1970s. (It was actually on the black market from Europe and Canada for a few years before the FDA approved its use in American products.)
Most recently, hyaluronic acid has been available as an oral supplement. Hyaluronic acid is particularly good for controlling pain, heat, and swelling.
An effective equine dose is between 100 and 200 mg/day.
100% Pure | FEMAS Assured
Suppelaze VS provides 2,000mg Vitamin C per 64g
Contributes to normal collagen formation for the normal function of cartilage, as well as the protectIon of cells from oxidative stress.
An effective equine dose for joint support is up to 2,000mg/day.
95% Pure | FEMAS Assured
Suppleaze VS provides 500mg Curcumin per 64g
Curcumin is the key active ingredient in turmeric and is 50 x stronger than Turmeric.
In its own right, Curcumin is known for its anti-inflammatory and antioxidant effect. Curcumin can reduce markers of inflammation and thus relieve osteoarthritIs symptoms and can even support wound healing through its antibacterial effects.
Suppleaze VS provides 12,300mg Boswellia per 64g
Also known as Frankincense, Boswelia is an effective joint aid long recognised for its anti-inflammatory benefits. Boswelia has a soothing influence on the digestive system which can help with loose droppings.
Bioactive Collagen Peptides (BCP)
Suppleaze VS provides 25,000mg Collagen Peptides per 64g
Specific, highly purified hydrolysed collagen peptides with a neutral taste and odour.
The average molecular weight is only 6.0 kDa for maximum absorption.
Collagen peptides are highly digestible and rapidly absorbed by the gastrointestinal tract and then into the bloodstream, significantly accumulatIng in cartilage and other connective tissues.
Collagen is the most abundant protein in the body and provides structure too much of the body including bones, skin tendons and ligaments.
There are many different types of Collagen, however, the most commonly researched include Types I, II and III (1,2 & 3). Type I is found in bones & skin and Type II is the main collagen of Cartilage, alongside proteoglycans including ChondroitIn sulphate.
Why add Bioactive Collagen Peptides to Suppleaze VS?
Your horse’s joints, which connect two or more bones, are mostly mobile allowing the bones to move in relationship to each other. The ends of the bones are covered by a smooth layer of articular cartilage, which is a smooth white tIssue, that allows the bones to glide over each other with very little friction.
ArtIcular cartilage consists of 60% type II Collagen, however, mutations/changes/depletion in type II collagen within the cartilage can result in several types of chondrodysplasia, leading to premature osteoarthritis. By adding Hydrolysed Collagen Peptides to Suppleaze VS, the aim is to diffuse the collagen back into the compromised articular cartilage.
Articular Cartilage does not contain blood flow so the cartilage cells are supplied by diffusion which makes the process of growth and repairs a much slower process.
What is special about Suppleaze VS Type II Collagen?
Suppleaze® Progen contains Bioactive Collagen Peptides® (BCP®), which are specific highly purified hydrolysed collagen peptides.
- BCP® is rapidly absorbed.
- Several clinical studies have demonstrated the efficacy of a BCP® treatment in the management of Osteoarthritis (OA).
- BCP® diminishes the degeneratIve process.
- BCP® enter the bloodstream and significantly accumulate in the cartilage and other connective tissues.
- BCP® can slow down the progression of Osteoarthritis (OA) and break the vicious cycle of joint degeneration.
- BCP® addresses the cause of the disease by stimulating joint cartilage metabolism.
- During Bioactive Collagen Peptides® research, 67% of horse owners assessed that 25g (BCP®) supplementation led to good treatment success for the osteoarthritis (OA) of their horses. This benefit was more pronounced by the administration of 50 g (BCP®) per day. 80 % of horse owners assessed the higher dosage as a successful treatment for their OA horses.
What does Hydrolysed Mean?
Hydrolysed means that the amino acid chains have been broken down into smaller units allowing the powder to dissolve easier.
What are Peptides?
A peptide is a short chain of two or more amino acids, which combine to form proteins within the body.
What is Hydrolysed Collagen?
HC is a group of peptides with a low molecular weight that can be obtained by enzymatic action in acid or alkaline media at a specific incubation temperature.
What sources can Hydrolysed Collagen be found?
HC can be extracted from different sources such as bovine or porcine.
How quickly will I notice a difference in my Horse?
Whilst most of the ingredients are activated by circulating the blood flow, the collagen needs to work it’s way into the cartilage by diffusion as there is no blood flow to this area.
Research suggests that it could take up to 6 weeks, however with the collagen working synergistically with the other ingredients, we feel that should notice a difference within 2 weeks.
How important is Vitamin C?
Vitamin C, Also known as ascorbic acid, is necessary for the growth, development and repair of all body Issues. It is involved in many body functions, including the formation of collagen, absorption of iron, the immune system, wound healing and the maintenance of cartilage, bones and teeth.
How does Vitamin C help my horse’s Collagen and HA intake?
Vitamin C has been shown to stabilise collagen mRNA, thus increasing collagen protein synthesis for repair. It has also been shown that Vitamin C is critical for the synthesis of Hyaluronic Acid that will speed up recovery time and relieve painful joints.