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Your dog's joints, which connect two or more bones, are mostly mobile allowing the bones to move in relationship to each other.
These joints are held together by the joint capsule which has a thin inner lining called the synovial membrane, which produces the synovial fluid to lubricate the joint.
The ends of the bones are covered by a smooth layer of articular cartilage, which is composed of specialised cells called Chondrocytes that produce a large amount of extracellular matrix (ECM). ECM is composed of two major components: 60% collagen (type II) & 30% proteoglycan (aggrecan). Cartilage does not contain blood vessels. The chondrocytes (cartilage cells) are supplied by diffusion; therefore, cartilage grows and repairs more slowly.
The chondrocytes are responsible for the anabolic and catabolic balance of cartilage metabolism.
The chondrocytes play a central role in the development because they are responsible for the anabolic and catabolic balance of cartilage metabolism. (Gelse et al. 2003; Bello & Oesser 2006).
Supplex Progen contains Hydrolysed Collagen and has a different method of action to most other joint supplements.
Based on current data*, the oral administration of Hydrolysed Collagen can help maintain joint health contributing towards preserving mobility and quality of life.
*Double-Blind, Placebo-Controlled Trial published in the American Journal of Animal and Veterinary Sciences: 2010.